Spravato (Esketamine)

A New Approach to Treatment-Resistant Depression

Spravato® (esketamine) is a prescription nasal treatment used in specific cases of depression, including treatment-resistant depression (TRD), under a monitored protocol.

It's designed for adults whose depression has not improved after multiple antidepressant trials (clinical determination required).

What is SPRAVATO® (esketamine) CIII nasal spray?

SPRAVATO® is a prescription medicine, used along with an antidepressant taken by mouth to treat:

Adults with treatment-resistant depression (TRD)

Depressive symptoms in adults with major depressive disorder (MDD) with suicidal thoughts or actions

Working with Your Healthcare Provider

Considering SPRAVATO®? The first step is talking to your healthcare provider. Get the facts and decide together if SPRAVATO® should be part of your overall treatment plan for your treatment-resistant depression.

Expect to review your overall medical and depression treatment history in deciding with your healthcare provider whether SPRAVATO® is right for you.

What to Discuss with your Healthcare Provider

Be sure to tell your healthcare provider if you have a history of abusing prescription or street drugs, or a problem with alcohol

Do not take SPRAVATO® if you have a blood vessel disease (aneurysm), an abnormal connection between your blood vessels (arteriovenous malformation), a history of bleeding in the brain or if you are allergic to esketamine, ketamine or any of the ingredients in SPRAVATO®

Be sure to tell your healthcare provider if you have heart, brain or liver problems; if you have psychosis; or if you are pregnant, planning to become pregnant, breastfeeding or planning to breastfeed. You should not take SPRAVATO® if you are pregnant.

Planning Your Treatment with SPRAVATO®

SPRAVATO® can only be administered under the supervision of a healthcare provider at a certified SPRAVATO® treatment center. Desert Bolt Behavioral is a REMS certified SPRAVATO treatment center. This could be a different location than your regular doctor’s office. Your healthcare provider will continue to be involved with your care during SPRAVATO® treatment and will be available to answer questions or address concerns as you undergo treatment.

If you are a new patient at Desert Bolt Behavioral, your first visit will be a consultation. The treatment center will:

receive your medical information from your healthcare provider

conduct its own assessment to determine if SPRAVATO® may be right for you

verify your insurance information as part of your eligibility confirmation

If SPRAVATO® is recommended, Desert Bolt Behavioral will build a treatment plan with you and enroll you in the SPRAVATO® REMS Program. You may start treatment on your next visit.

What to Expect

  • Initial Consult: review history, prior treatments, medical considerations, and eligibility pathway

  • Treatment: in-office administration with monitoring per protocol

  • Follow-up symptom tracking and ongoing evaluation

  • Coordinated care with your existing treatment team

Is Spravato® Right for You?

Spravato® may be appropriate if you have been diagnosed with major depressive disorder and have not responded adequately to at least two different antidepressant treatments. Eligibility is determined through a thorough clinical evaluation.

Contact us to schedule a consultation and discuss whether Spravato® may be a good fit for your treatment plan.

42201 N 41st Dr building b suite 160, Anthem, AZ 85086, USA

Visit Us

At Desert Bolt®, we value the state of mind of our clients. Patients are often the first to detect a change in their wellbeing. We are here to listen to you, and help you maximize your full potential. Our Nurse Practitioner and therapists provide client-centered care. This means everything we do is about you, not us.

Anthem & North Phoenix, AZ

Desert Bolt Behavioral

Outpatient psychiatric care and psychotherapy for adults and teens in Anthem & North Phoenix, AZ.

Quick Links

Services

Conditions We Treat

ADHD Evaluation

Spravato® Treatment

About Us

FAQ

© Copyright 2026. Desert Bolt Behavioral